J.J.CORP Solution

When it comes to filling biopharmaceutical active ingredients, a different solution is needed compared to conventional pumps. JJ Corp offers a peristaltic technology that is highly precise and safe for the product. The pump only comes into contact with the tubes, so it is well-suited for single-use filling systems. This technology can fill volumes ranging from 50 microliters to three milliliters, making it a flexible and secure solution for highly potent pharmaceuticals.

• The pump head, housing, and rotor with rollers of our peristaltic technology are made of stainless steel (316L).
• This technology is especially appropriate for aqueous solutions and biotech products.
• The product path, which includes the tubing, is fully replaceable, making it a single-use system.

This system has gained popularity worldwide, after being widely used for filling operations in the US. It allows for safe and closed low-shear filling through a rolling diaphragm, making it especially suitable for challenging water-like liquids that are prone to cross-contamination, leakage, and difficulty in cleaning and sterilization.

Additionally, this pump offers versatility and is available in both stainless steel and single-use variants, making it ideal for flexible small-batch production.

• Utilizes a closed filling mechanism
• Easy to clean and sterilize
• Capable of delivering precise and consistent fill volumes

To accurately fill both aqueous solutions and highly viscous liquids, the rotary valve piston pump is a versatile option. It is simple to use and precise, making it suitable for products that are not affected by shear.

The filling system can be customized in terms of design, available in both stainless steel and ceramic options. Additionally, the rotary valve piston pump is compatible with Smart Pump, our Industry 4.0 solution, allowing for easy integration.

• Features servo drive for exceptionally high precision
• Quick assembly with minimal seals required
• Can be easily cleaned and sterilized through CIP/SIP processes

The Smart Pump is our cutting-edge technology that provides enhanced transparency of process data. It utilizes advanced RFID technology to transfer crucial parameters such as pump position, cleaning status, and correction value from the piston pump to the filling machine. Each filling point is equipped with a RFID reader to enable visualization of the data on the control panel of the filling machine. The RFID tag integrated into the system stores all information.

• Detection of errors at an early stage
• Ensures process safety
• Reproduces parameters accurately

For accurate filling operations, mass-flow technology is ideal. The system is closed and includes sensors that measure the volume flow, ensuring that the filling quantities are precisely dosed. In addition to filling accuracy, mass-flow can handle hot or cold filling, making it suitable for processing X-ray contrast media, among other things.

• Quick CIP/SIP processes
• Highly accurate dosing
• Integrated 100% in-process control (IPC)

To fill challenging products such as suspensions or crystallizing liquids, a closed and easy-to-clean system is required, such as JJ Corp’s time-pressure filling system. Advanced algorithms enhance the accuracy of the filling process. Mechanically, time-pressure filling provides maximum product yield as the filling sections can be completely emptied.

Benefits:

• Achieves high precision and productivity.
• Features a user-friendly overall geometry.
• Enables easy assembly and format changes.

Achieving versatility in filling multiple products with varying properties can be done without requiring different systems. JJ Corp’s patented combi approach offers flexibility on a single platform that integrates up to four filling stations, including peristaltic, rotary valve piston, rolling diaphragm pump, and time-pressure filling. This approach facilitates frequent and short product changeovers, making it ideal for settings with limited space and high flexibility requirements. Furthermore, the system enables easy assembly and format changes.

• The filling line allows for a variable number of filling stations, offering flexibility for different production needs.
• The layout of the filling line is both flexible and space-saving, making it suitable for a range of production settings.
• The filling line can be configured for use with either stainless steel or single-use systems.